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Guide to Diabetes

Hormone Replacement Therapy or HRT

Middle aged women sat on a bench
HRT is the replacement of the female hormone oestrogen in women with low levels.

Why replace hormones?

HRT maybe considered in three circumstances:

  • After the natural menopause, which occurs around the age of 50 years and which is due to the failure of the function of the ovaries themsleves, which can no longer produce oestrogen.
  • After ovarian failure occuring at a younger age than the normal menopause. This may be because the ovaries were never able to function normally, when previously normal ovaries stop functioning known as “Premature Ovarian Failure” or “Premature Menopause”, or when normal ovaries are removed surgically or damaged by radiotherapy or chemotherapy given for other reasons.
  • In hypopituitarism when the pituitary control hormones Lieutenising Hormone (LH) and Follicle Stimulating Hormone ( FSH) are deficient and are no longer stimulate the ovaries to produce oestrogen.

Written by Dr Trevor A. Howlett, MD FRCP Consultant Physician & Endocrinologist. For more information download the leaflet below. (1)

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